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Archive for October, 2010

Newsflash: More Fish Oil Fodder

“Contrary to popular belief, fish oil is scientifically proven only to cause pharmacological overdoses to blood plasma DHA/EPA levels. IF these overdoses were anything good, one would certainly see the supposed positive enhanced “brain effects” and positive cardiovascular/anti-cancer effects were quickly. This October 2010 Wall Street Journal article shows fish oil failure once again…..pregnant women should not consume fish oil unless they wish a caesarean section. Again, would a proper nutritional supplement be excellent for both mom-to-be and baby-to-be? Of course, it should. Fish oil is out once again…..”

1)  http://topics.wsj.com/article/SB20001424052702303550904575562053166893846.html 

 By SHIRLEY S. WANG

 Fish-oil supplements don’t appear to help pregnant women prevent post-partum depression or boost the baby’s brain development as previously believed, according to a large trial published Tuesday in the Journal of the American Medical Association.

The 2,400-woman, randomized study complicates the advice for pregnant women. It adds to a body of mixed research on some potential benefits of the popular omega-3 fatty acid known as DHA, or docosahexaenoic acid. DHA, which can move from the mother to the baby during pregnancy, accumulates in the brain and is thought to be involved in helping brain cells communicate.

In general, for healthy women with normal pregnancies, “[DHA] supplementation will actually not give you a huge benefit in terms of neurodevelopmental outcomes and reducing depressive symptoms,” said Maria Makrides, an author on the study and deputy director of the Women’s and Children’s Health Research Institute in North Adelaide, Australia.

The results are “disappointing,” said Emily Oken, a professor of population medicine at Harvard Medical School and Harvard Pilgrim Health Care Institute, who wrote an editorial to accompany the paper but wasn’t involved in the study. But “it doesn’t mean we should give up on fish or fish oil during pregnancy,” she said.

Several previous studies have shown that eating fish during pregnancy helped in the baby’s brain development and in reducing the risk of post-partum depression. That research, however, typically didn’t involve randomized, controlled studies. Instead, women were asked whether or not they chose to eat fish during pregnancy.

It could be the case that eating fish is better than taking fish-oil supplements or that women who opt to eat fish are generally healthier and engage in other health-promoting behaviors, Dr. Oken said. The few trials conducted that separated participants, into a group taking fish-oil supplements and another that didn’t, weren’t well done, because the women often knew if they were getting the supplement, and in some cases there wasn’t a comparison group at all, she said.

The latest study does suggest that some subgroups of women might benefit from fish-oil supplements. For instance, those with a history of clinical depression—and thus are at higher risk of post-partum depression—who took 800 milligrams [bp NOTE: still a tremendous amount and results would show ….IF it worked, that is] of fish oil daily lowered their risk of getting depressed after the birth by about 4% compared with those who didn’t take fish oil.

However, the difference wasn’t statistically significant [bp NOTE: that is WRONG —  IF it really worked only a small number are needed!] because of the small number of women in the study who had been previously depressed, said Dr. Makrides, who is also a professor of human nutrition at the University of Adelaide.

Women in the fish-oil group had lower rates of pre-term births, particularly births earlier than 34 weeks of gestation. But, there was a trade-off: More women who took the supplement needed their labor to be induced or had caesarean sections because the babies stayed in the womb longer,[bp NOTE: an awful effect!]  said Dr. Makrides.

Additional research is needed to study the benefits of targeting DHA supplements to women with a history of depression or who previously had a premature baby, according to Dr. Makrides. However, all pregnant women should strive for balance [bp NOTE: weasel words] and eat a variety of foods, including fish, she said.

Omega-3 fatty acids are the fourth most common supplement after multivitamins, calcium and vitamin C, according to the Council for Responsible Nutrition, an industry trade group.

Other health benefits have been attributed to omega-3s. Research suggests they lower triglyceride fat levels [bp NOTE: irrelevant!] and are likely helpful [bp NOTE: great wording…. more weasel words] in preventing heart disease, according to the National Institutes of Health. There is some evidence [bp NOTE: i have some evidence that gravity pulls you UP….., too.]  omega-3s also may help decrease blood pressure, improve thinking in kids with attention deficit-hyperactivity disorder, help with weight loss and reduce the risk of endometrial cancer. Fish oil doesn’t seem to help lower blood sugar for diabetics, however, and there isn’t enough research to conclude effectiveness for conditions such as Alzheimer’s disease, irregular heart beat and cancer, according to the NIH. [bp NOTE: jesus….help all the poor misled people ……]

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Parent to Derivative EFA Ratios – The conversion is MUCH LESS than Everyone States

The major metabolic route of ALA (parent omega-3) in the body is beta-oxidation. This means that parent omega-3 is mainly burned for energy – not incorporated into cellular structure or used for derivatives – your body requires very little and will attempt to remove an excess if it can. ONLY VERY LITTLE PARENT OMEGA-3 IS REQUIRED FOR PROPER CELL MEMBRANE STRUCTURE. However, if you are “overdosing” from supplements, based on incorrect advice [which is MOST of the current advice on the market], the excess will be forced into the cell structure as the “Lipids 2000” medical journal states:

“Linoleic acid (LA parent omega-6 FA) accumulates throughout the body of most mammals, whereas alpha-linolenic acid [ALA parent omega-3] is rarely found in those tissues to the same extent as LA”, “Increased alpha-linolenic acid [parent omega-3] intake increases tissue alpha-linolenic content [parent omega-3]” (Lipids 2000 Apr; 35(4):395-400.

This will NEGATIVELY IMPACT your cancer defense.

ALA accumultes in specific sites in the body of mammals, and only a small portion of dietary ALA is converted to DHA (Sinclair, A.J., et al., “What is the role of alpha-linolenic acid for mammals,” Lipids 2002 Dec;37(12):113-23).

The next piece of shocking information is from the “PUFA Newsletter”. “Alpha-Linolenic Acid Conversion Revisted” by Norman Salem et al., states,

“A recent article in the PUFA [Polyunsaturated Fatty Acid] Newsletter indicated that in adult men and women the ‘average estimated conversion of … alpha-linolenic acid to n-3-LC-PUFA metabolites and docosahexaenoic acid [DHA] was 17.3 +/- 12.8 and 3.6 +/- 3.8 percent, respectively (mean + SD)’. This is likely to be an OVERESTIMATE of the actual overall conversion rates for several reasons. We see even with this excessive estimate of the parent omega-3 derivative conersion that theoretically no more than 37% of them are converted to derivatives.”

The article makes the case that in reality only about 5% of the parent ALA [omega-]) is converted into derivatives. Pawlosky and others calculate that less than a mere 1% goes to derivatives. The article ends with, “The best estimates of alpha-linolenic acid conversion to n-3 LC-PUFA are much smaller than those claimed…”

Omega-6 conversion is also overstated:

“… Linking LA and AA in this way also implies a direct conversion of LA [parent omega-6] to AA [omega-6 derivative] which is not the case. In fact, a very high dietary LA will reduce membrane AA [the opposite effect!].” Note: This is why it was reported in the article by S. Bunting, s. Moncada, and J.R. Vane, titled “Prostacyclin – Thromboxane A2 Balance: Pathophysiological and Terapeutic Implications,” ‘British Medical Journal’, (1983)Vo.39, No.3, pages 271-276, that “AA in the phospholipids of Eskimo [consuming lots of parent omega-6] is approximately ONE-THIRD of that in Danes.”

The above quote was taken from Crawford, M.A., “Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids,” in ‘Prostaglandins Leukot Essent Fatty acids 2000 Sep;63(3):131-4.

Here is the takehome to all the science above:

TOO MUCH OMEGA-3, OMEGA DERIVATIVES, OR DEFECTIVE EFAS RUIN THE CELL MEMBRANE STRUCTURE AND MINIMIZE YOUR LEVEL OF ANTICANCER PROTECTION.

Remember your goal is to MAXIMIZE the cell membrane structure so that the cells can remain fully oxygenated (cellular oxygenation), thus preventing a drop in cellular oxygenation of 30% which is the threshhold that Dr. Otto Warburg showed over and over again that healthy cells convert to cancer cells and cannot be reconverted.

So… when you are supplementing with Parent Essential Oils, PLEASE be sure you find a blend with the PROPER balance of Omega-6 and Omega-3 (2.5:1 to 1:1) or you could inevitably be negatively affecting your health and cancer prevention.

You can read more about this in much more detail in my book, “The Hidden Story of Cancer”, which can be ordered through the following website: http://www.brianpeskin.com.