Archive

Posts Tagged ‘respiration’

Excerpt from “On the Origin of Cancer Cells”, Science, February 1956, Volume 123, Number 3191

March 22, 2010 1 comment

The following was written by Dr. Otto Warburg (comments inserted by Professor Peskin as “bp”)

For more of this information, please read, “The Hidden Story of Cancer” (www.brianpeskin.com).

**********

Cancer cells originate from normal body cells in TWO PHASES. The first phase is the IRREVERSIBLE INJURING OF RESPIRATION. Just as there are many remote causes of plague – heat, insects, rats – but only one common cause, the plague bacillus, there are a great many remote causes of cancer – tar, rays, arsenic, pressure, urethane – BUT THERE IS ONLY ONE COMMON CAUSE INTO WHICH ALL OTHER CAUSES OF CANCER MERGE: THE IRREVERSIBLE INJURING OF RESPIRATION.

(bp: Dr. Warburg makes it clear that cancer has but one primary cause, and all other effects lead to this prime cause.)

The irreversible injuring of respiration is followed, as the second phase of cancer formation, by a long struggle for existence by the injured cells to maintain their structure, in which a part of the cells perish from lack of energy, while another part succeed in replacing the irretrievably lost respiration energy by fermentation energy.

Because of the morphological inferiority of fermentation energy, the highly differentiated body cells are converted by this into undifferentiated cells that grow wildly – the cancer cells.

To the thousands of quantitative experiments on which these results are based, I should like to add, as a further argument, the fact that there is no alternative today. If the explanation of a vital process is its reduction to physics and chemistry, there is today no other explanation for the origin of cancer cells, either special or general.

(bp: Thousands of experiments confirm Dr. Warburg’s conclusions.)

From this point of view, mutation and carcinogenic agent are not alternatives, but empty words, unless metabolically specified. Even more harmful in the struggle against cancer can be the continual discovery of miscellaneous cancer agents and cancer viruses, which, by obscuring the underlying phenomena, may hinder necessary preventive measures and thereby become responsible for cancer cases.

******

Harvard Professor Lewontin eategorically states that genetic causes are meaningless unless a metabolic pathway is specified and understood. Dr. Warburg knew of, and stated this same insight earlier, in 1955.

Dr. Warburg’s Conclusions:

* Mutation (the “genetic theory”) is not cancer’s cause.

* Supposed carcinogenic agents (other than oxygen deprivers) are not cancer’s cause.

Dr. Warburg warns here that researchers looking into genetic causes or various non-specific carcinogens will bring forth no significant results because they are not the true direct cause of cancer. Valuable time has been wasted in these fruitless searches.

But apparently, no one has listened. We keep hearing about the so-called genetic “predisposition”, the “viral” possibility, the DNA “mutation”. Dr. Warburg made it clear that those “researching” these areas are wasting precious time, hindering protective measures, and indeed, becoming responsible for causing more cancer cases…

See the full explanation in “The Hidden Story of Cancer” by Professor Brian Peskin. You can get a copy at http://www.brianpeskin.com.

Advertisements

Adenosine Triposphate = Adenosine Triphosphate. Or Does it?

February 15, 2010 Leave a comment

In his research on the mechanism of cellular energy production difference between normal cells and cancerous cells, Dr. Warburg poses a most important question: Why does fermentation cause cancer cells to dedifferentiate and lose intelligence? Or to put it another way, why are the body cells dedifferentiated when their respiration energy (produced in the presence of oxygen) is replaced by fermentation energy (produced in the absence of oxygen)?

At first, one would think that it is immaterial to the cells whether they obtain their energy from respiration or from fermentation, since the energy of both reactions is transformed into the energy of adenosine triphosphate, and yet adenosine triphosphate = adenosine triphosphate. This equation is certainly correct chemically and energetically, but it is incorrect morphologically because although respiration takes place for the most part in the structure of the grana (mitochondria), the fermentation enzymes are found for a greater part in the fluid protoplasm. The adenosine triphosphate synthesized by respiration therefore involves more (cell) structure than adenosine triphosphate synthesized by fermentation.

Thus, it is as if one reduced the same amount of silver on a photographic plate by the same amount of light, but in once case with diffused light and in the other with patterned light. In the first case, a diffuse blackening appears on the plate, but in the second case, a picture appears; however, the same thing happens chemically and energetically in both cases. Just as the one type of light energy involves more structure than the other type, the adenosine triphosphate energy involves more structure when it is formed by respiration than it does when it is formed by fermentation.

IN OTHER WORDS, normal cell respiration takes place in the presence of a more differentiated cell structure; cancer cells’ respiration of fermation involves less structure.

…….

This gets a little complicated here so you can read further (with real life examples) in “The Hidden Story of Cancer” (www.brianpeskin.com ).

Let me present you with an excellent example showing how all energy isn’t created equal, as Dr. Warburg explains:

Convection energy produced from your conventional oven produces a uniformly warm product. However, placing the same item in a microwave energy oven often produces extremely dangerous “hot spots” with “cold spots” nearby. The two heating methods work very differently, just like energy produced from fermentation is different than energy produced with oxygen!

Learn more in “The Hidden Story of Cancer”. You can get your copy from www.brianpeskin.com.